When the colonisers travelled from England to Jamestown, they were hit with a hurricane, and so their food stores were depleted, leaving them very very hungry.
After eating their horses, dogs, cats, rats, and boots, some turned to cannibalism. There are eyewitness accounts that recall people digging up graves, and there was one story about a man who killed and ate his pregnant wife.
If that wasn’t disturbing enough, in 2013, the body of a 14-year-old-girl who had been murdered and cannibalised was discovered. The details are pretty sickening, so read at your own risk.